Cannabinoids Relieve Symptoms Of Endometriosis

Endometriosis is an often painful disorder in which tissue that normally lines the inside of your uterus — the endometrium — grows outside your uterus (endometrial implant). Cannabinoids appear to have a favorable action in limiting cell proliferation and in controlling pain symptoms of endometriosis.
Aug 22, 2017

Endometriosis is an often painful disorder in which tissue that normally lines the inside of your uterus — the endometrium — grows outside your uterus (endometrial implant). The tissue growth (implant) typically occurs in the pelvic area, outside of the uterus, on the ovaries, bowel, rectum, bladder, and the delicate lining of the pelvis. However, the implants can occur in other areas of the body, too.

Each month a woman’s ovaries produce hormones that stimulate the cells of the uterine lining (endometrium) to multiply and prepare for a fertilized egg.  The lining swells and gets thicker. If these cells (called endometrial cells) grow outside the uterus, endometriosis results.  Unlike cells normally found in the uterus that are shed during menstruation, the ones outside the uterus stay in place. They sometimes bleed a little bit, but they heal and are stimulated again during the next cycle.

This ongoing process leads to symptoms of endometriosis (pain) and can cause scars (adhesions) on the tubes, ovaries, and surrounding structures in the pelvis.

The cause of endometriosis is unknown, but there are a number of theories.  One theory is that the endometrial cells loosened during menstruation may “back up” through the fallopian tubes into the pelvis. Once there, they implant and grow in the pelvic or abdominal cavities.  This is called retrograde menstruation.  This happens in many women, but there may be something different about the immune system in women who develop endometriosis compared to those who do not get the condition.

Endometriosis is a common problem.  Sometimes, it may run in the family.  Although endometriosis is typically diagnosed between ages 25 – 35, the condition probably begins about the time that regular menstruation begins.

Endometriosis and Medical Cannabis

Extensive medical and scientific evidence that demonstrates that the cannabinoids contained in the cannabis plant.(phytocannabinoids) can ease the majority of the symptoms caused by endometriosis, such as pain, depression, headache, hypoglycemia, anxiety, fatigue, inflammation, and many others.

Research indicates that cannabidiol (CBD), the non-psychoactive component of cannabis, is responsible for the reduction of inflammation associated with chronic inflammatory states, as demonstrated in a 2004 study by Italian researchers from the University of Milano-Bicocca. In the case of endometriosis, the cells that line the uterus (the endometrium) are present outside of it and can bleed, releasing inflammatory mediators and causing localised pain. The administration of cannabidiol greatly improves the patients’ quality of life because they can control the pain, and even completely stop taking any other medicine.

2012 review examined 8 studies on the endocannabinoid system and endometriosis  and concluded that cannabinoids “appear to have a favorable action in limiting cell proliferation and in controlling pain symptoms” of endometriosis. Another review, from 2013, expands to the focus to the female reproductive organs as a whole and reaches a similar conclusion: “it is possible to speculate that reduced cannabinoid signalling might underlie the enhanced proliferative capacity of endometriotic lesions.”


It is very important that women with endometriosis on hormonal treatments do not SMOKE, and this also means smoke cannabis. Smoking increases your risk of deadly blood clots – If you prefer to inhale rather than eat your cannabis, please vape.

Vaporizing cannabis is better than smoking cannabis in a joint, pipe, or bong because it doesn’t burn the cannabis. Smoking cannabis releases toxins similar to cigarettes, can cause lung irritation and often disintegrates cannabinoids with healing properties. Vaporizing cannabis heats the air around the cannabis, releasing a range of cannabinoids, each with unique health benefit. Cannabis oil are highly recommended as well as topical creams to help ease pain around the pelvic area and back. Juicing raw cannabis may reduce pain and inflammation associated with endometriosis, without that high you get from heated cannabis. That’s because raw cannabis has THCA and CBDA, the non-psychoactive forms of THC and CBD. Juice strains of cannabis with high levels of CBD(A) for best results. We’re especially excited about this new method, as daily juicing may cause remission of endometriosis. Women with endometriosis are also encouraged to avoid chemicals in their food, hair and beauty products, and environment in addition to using cannabis therapy. Go green!

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All information on this page is subject to MCDSA’s disclaimer.


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